Blar i NTNU Open på forfatter "Delaney, Kamila"
-
Splice site m<sup>6</sup>A methylation prevents binding of U2AF35 to inhibit RNA splicing
Mendel, Mateusz; Delaney, Kamila; Pandey, Radha Raman; Chen, Kuan-Ming; Wenda, Joanna M.; Vågbø, Cathrine Broberg; Steiner, Florian A.; Homolka, David; Pillai, Ramesh S. (Journal article; Peer reviewed, 2021)The N6-methyladenosine (m6A) RNA modification is used widely to alter the fate of mRNAs. Here we demonstrate that the C. elegans writer METT-10 (the ortholog of mouse METTL16) deposits an m6A mark on the 3′ splice site ...